Structure and function of the Hippo pathway. (A) Hippo pathway in D. melanogaster (from  with permission). (B) A wildtype (left) and an overgrown (right) Drosophila eye caused by a hippo mutation (from  with permission). (C) Mouse livers from a control (left) and an individual with dysregulated Hippo signaling (right) (from  with permission).
Zhu et al. BMC Evolutionary Biology 2013 13:76 doi:10.1186/1471-2148-13-76