Open Access Research article

Evidence of recent natural selection on the Southeast Asian deletion (--SEA) causing α-thalassemia in South China

Qin-Wei Qiu1, Dong-Dong Wu2, Li-Hua Yu1, Ti-Zhen Yan3, Wen Zhang45, Zhe-Tao Li1, Yan-Hui Liu1, Ya-Ping Zhang2 and Xiang-Min Xu1*

Author Affiliations

1 Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, P.R. China

2 State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, P.R. China

3 Clinical Laboratory, Liuzhou Municipal Maternity and Child Healthcare Hospital, Liuzhou, Guangxi, 545001, P.R. China

4 Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, 650223, China

5 Graduate School of the Chinese Academy of Sciences, Beijing, 100039, China

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BMC Evolutionary Biology 2013, 13:63  doi:10.1186/1471-2148-13-63

Published: 11 March 2013

Additional files

Additional file 1:

List of the 28 SNPs, their indentifiers, the primers used for prior-HRM amplification of them. The sequences are shown from 5′ to 3′ end.

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Open Data