Open Access Highly Accessed Research article

Evolution of Escherichia coli rifampicin resistance in an antibiotic-free environment during thermal stress

Alejandra Rodríguez-Verdugo12, Brandon S Gaut1 and Olivier Tenaillon23*

Author Affiliations

1 Department of Ecology and Evolutionary Biology, UC Irvine, Irvine, CA, USA

2 INSERM, Université Paris7, Faculté de Médicine Denis Diderot, UMR-S 722, Paris, France

3 INSERM UMR-S 722, Université Paris7, Faculté de Médicine Denis Diderot, Site Xavier Bichat, 16 rue Henri Huchard, 75018, Paris, France

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BMC Evolutionary Biology 2013, 13:50  doi:10.1186/1471-2148-13-50

Published: 22 February 2013

Additional files

Additional file 1:

Parameters of fixation.

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Additional file 2 Table S1:

Oligonucleotides and primers used in this study.

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Additional file 3 Table S2:

Parameters of fixation estimated from the frequency trajectories.

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Additional file 4 Table S3:

Relative fitness measured in different conditions and different genetic backgrounds.

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Additional file 5:

Three-dimensional structure of RNAP generated using Jmol from the Protein Data Bank (http://www.rcsb.org webcite).

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