Amino acid sequence logos of P. caudatum Hsp70 motifs. (A) putative ATP/GTP-binding site motif A (P-loop), (B) Hsp70 family signature 2, (C) putative bipartite nuclear localization signal, (D) potential signature for eukaryotic non-organellar Hsp70 proteins, and (E) Hsp70 family signature 3. The size of each letter is proportional to the frequency of occurrence of the respective amino acid in a multiple sequence alignment. The letters are sorted with the most frequent one on top and the overall height of each stack indicates the information content of the sequence at the given position (0–4 bits). The sequence logos were prepared from sequences of all P. caudatum hsp70s (A,B,E), from the cytosolic and ER-type homologs (D), and from the cytosolic hsp70 genes only (C).
Krenek et al. BMC Evolutionary Biology 2013 13:49 doi:10.1186/1471-2148-13-49