Additional file 4.

Alignment of FGF5 amino acid sequences determined for the seven cetaceans in this study and other terrestrial mammals in GenBank and Ensemble Genome database. The signal peptide and the glycine box are highlighted in blue and green, respectively. Black triangles depict O-glycosylation sites and a green vertical arrow is used to depict the N-glycosylation site. The FGF receptor (FGFR) and the heparin binding sites are indicated with red circles and red triangles, respectively [44]. Amino acid residues under positive selection in toothed whales and baleen whales are highlighted in red and yellow, respectively.

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Chen et al. BMC Evolutionary Biology 2013 13:34   doi:10.1186/1471-2148-13-34