Relationship between genomic GC content and concordance of overall amino acid composition and sense codons. The concordance was weighed by the Pearson correlation coefficient (r) between the frequencies of the 20 amino acids and the corresponding synonymous codon frequencies based on the universal genetic code. A parabolic model was used to simulate the trend of the concordance against GC content.
Chen et al. BMC Evolutionary Biology 2013 13:219 doi:10.1186/1471-2148-13-219