Domain organisation of class XI myosins. Land plant class XI myosins are composed of an N-terminal SH3-like domain, the myosin head domain, 6 IQ motifs, a coiled-coil region with unique parts of variable length and a C-terminal DIL domain. The C-terminal DIL domain was lost in most myosins of subtype 11D and in some algae class XI myosins. The domain organisations of the different subtypes are illustrated by Brassica rapa (Brsp) myosins. Myosins of the green algae, e.g. Volvox carteri f. nagariensis (Vc) and Asterochloris sp. Cgr/DA1pho (Ahs), show different domain compositions with respect to the number of IQ motifs. VcMyo11B has also lost the C-terminal DIL domain like the myosin-11D homologs. A consensus domain composition is depicted in the lowermost scheme (Myo11 consensus). All domain schemes are drawn to scale. Numbers at the C-termini denote the lengths of the respective sequences.
Mühlhausen and Kollmar BMC Evolutionary Biology 2013 13:202 doi:10.1186/1471-2148-13-202