Figure 5.

Sensitivity of bacterial adaptation on rugged-slope landscapes to presence and specificity of coevolving phage. Rows from top-to-bottom show increasing ruggedness (decreasing span). In each row, plots show: Left: Example of adaptive landscape, plotting maximum growth rate (δγ) as a function of genotype (blue solid line) and the growth rate of the initial bacterial genotype (black dashed line). Middle: Frequency distribution of highest maximum growth rates in final populations for bacteria evolving alone. Right: Frequency distribution of highest maximum growth rates in final populations for bacteria coevolving with phage, as a function of specificity of phage (s). See text for details of method. Ensemble sizes {35,33,20,20} for span={1,3,5,7} respectively. Parameter settings as Table 1 except for manipulated s, MB=MV=10−5and Vinit=0 for no-phage treatments.

Williams BMC Evolutionary Biology 2013 13:17   doi:10.1186/1471-2148-13-17
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