Additional file 5.

Figure S4 CHEF karyotypes in three experimental populations after 400 generations of nitrogen-limited, glucose-sufficient culture with increasing ethanol. At left are the karyotypes of parental strains, S. cerevisiae CEN.PK, S. uvarum CBS7001, and their F1 interspecific hybrid. 7 random clones were isolated from each experimental population. Green arrows indicate karyotypic variability in experimental populations. Medium ethanol content at 400 generations was 14%.

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Piotrowski et al. BMC Evolutionary Biology 2012 12:46   doi:10.1186/1471-2148-12-46