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Open Access Highly Accessed Research article

Adaptive evolution and functional constraint at TLR4 during the secondary aquatic adaptation and diversification of cetaceans

Tong Shen, Shixia Xu, Xiaohong Wang, Wenhua Yu, Kaiya Zhou and Guang Yang*

Author Affiliations

Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China

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BMC Evolutionary Biology 2012, 12:39  doi:10.1186/1471-2148-12-39

Published: 24 March 2012

Additional files

Additional file 1:

Table S1 Information about 17 representative cetaceans and some relative even-toed ungulates.

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Additional file 2:

Table S2 Detailing the results of branch-site model analysis for positive selection at cetacean TLR4.

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Additional file 3:

Table S3 Primers amplifying the complete ORF of representative cetaceans and some relative even-toed ungulates TLR4.

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