Correction: Proportionality between variances in gene expression induced by noise and mutation: consequence of evolutionary robustness
Department of Basic Science, Univ. of Tokyo 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan
BMC Evolutionary Biology 2012, 12:240 doi:10.1186/1471-2148-12-240Published: 9 December 2012
First paragraph (this article has no abstract)
Although the simulation data as well as the conclusion on the proportionality between Vip(i) and Vg(i) in the work  is correct, interpretation of some data therein should be corrected. As the sampling number (L = 200) to measure the average gene expression level is not large enough, there is a bias in the estimate in Vg(i). Finiteness in the number of sampling L will generally cause a bias of the order of Vip(i)/L, in the estimate of the variance Vg(i). The too good proportionality between Vip(i) and Vg(i) for large σ, shown in Figure two (a)(b) of  (especially for small Vg(i)), is due to this artifact. Accordingly, the sharp peak at ∼1/L = 1/200 in Figure three of  is due to this insufficiency by the sample number.