Evolutionary relationships between analyzed species. The JTT matrix-based method  is used to compute the evolutionary distances and the phylogenetic tree is constructed using the Neighbor-Joining method . Bootstrapping values from 500 replicates are shown and selected taxon information is depicted on the right. Species abbreviations are as follows: AQ: Amphimedon queenslandica (sponge), DM: Drosophila melanogaster (fruit fly), HM: Hydra magnipapillata (hydra), HS: Homo sapiens (human), NV: Nematostella vectensis (sea anemone), SP: Strongylocentrotus purpuratus (sea urchin).
Ryu et al. BMC Evolutionary Biology 2012 12:236 doi:10.1186/1471-2148-12-236