Table 1

Paired tests comparing upstreamgenes with their downstreamtargets
Parameter na Upstream > Downstreamb Upstream < Downstreamc P
ω 800 446 352 0.001***
dN 800 450 348 3.50×10–4***
dS 800 429 370 0.040*
Expression level 763 357 406 0.082
Expression breadth 763 261 337 0.002**
ENC 800 398 402 0.916
Connectivity 709 230 456 8.66×10–18***
Number of paralogs 800 369 373 0.912

*, P<0.05; **, P<0.01, ***, P<0.001.

aNumber of genes with at least one direct downstream target (out-degree>0). Only genes with available information for the parameter of interest were considered.

bNumber of genes with a higher value than the central value of its downstream targets.

cNumber of genes with a lower value than the central value of its downstream targets.

Alvarez-Ponce

Alvarez-Ponce BMC Evolutionary Biology 2012 12:192   doi:10.1186/1471-2148-12-192

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