Comparison of snoRNAs traceable to LECA (Figure1) and those experimentally characterised 2'-O-methylation sites attributable to LECA based on conservation between Arabidopsis thaliana (At) and at least one of Homo sapiens (Hs) and Saccharomyces cerevisiae (Sc). Using these independent lines of evidence, 25 families can be placed in the LECA. Plant snoRNAs are not always recognized by Rfam models for the equivalent animal snoRNA, suggesting that Rfam coverage is currently incomplete (Figure 4; light-grey boxes). Two of the snoRNAs listed here (U3, U13) do not function as modification guides and therefore cannot be mapped to existing sites.
Hoeppner and Poole BMC Evolutionary Biology 2012 12:183 doi:10.1186/1471-2148-12-183