Open Access Research article

Convergent evolution of modularity in metabolic networks through different community structures

Wanding Zhou1 and Luay Nakhleh2

1 Department of Bioengineering, Rice University, Houston, TX, USA

2 Department of Computer Science, Rice University, Houston, TX, USA

BMC Evolutionary Biology 2012, 12:181 doi:10.1186/1471-2148-12-181

Published: 14 September 2012

Additional files

Additional file 1:

Supplementary Material. A pdf file compiling additional Figures and Tables referred in the text.

Format: PDF Size: 3.3MB Download file

This file can be viewed with: Adobe Acrobat Reader

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Additional file 2:

Representative cases in pathway-community comparison. A Microsoft Excel table showing pathway community overlaps with high pathway specificity or community specificity.

Format: XLS Size: 271KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 3:

Clusters of species by community structure similarity. A Microsoft Excel table showing the clusters of species obtained by hierarchical clustering of species under the distance that equals to 1 - mutual information.

Format: XLS Size: 26KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 4:

Overview of organisms and modularities. A Microsoft Excel table showing the list of organisms, their lifestyle classifcations and computed modularity score, both normalized and unnormalized and from four different network reconstructions.

Format: XLS Size: 28KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data