Table 1

Enrichment of gene ontology (GO) terms in genes that were differentially expressed during heat stress
Enriched in SD
GO-ID Category: Term % sequences within group* FDRP-value
differentially expressed non-changing
0006950 P: response to stress 24.07 2.47 3.94 x 10-5
0042302 F: structural constituent of cuticle 9.84 0.19 3.94 x 10-5
0008199 F: ferric iron binding 4.69 0.01 0.00592
0006826 P: iron ion transport 4.69 0.03 0.00630
0006879 P: cellular iron ion homeostasis 4.69 0.03 0.00630
0005524 F: ATP binding 31.37 7.52 0.00880
0051093 P: negative regulation of developmental process 8.06 0.48 0.01300
Enriched in SC
GO-ID Category: Term % sequences within group*# FDRP-value
differentially expressed non-changing
0005319 F: lipid transporter activity 4.46 0.11 1.27 x 10-8
0006869 P: lipid transport 4.46 0.23 1.50 x 10-6
0033279 C: ribosomal subunit 6.36 1.24 7.46 x 10-4
0032982 C: myosin filament 2.63 0.25 0.01390
0008199 F: ferric iron binding 1.74 0.07 0.01914
0006879 P: cellular iron ion homeostasis 1.74 0.08 0.02918
0006414 P: translational elongation 3.54 0.62 0.03517
0003677 F: DNA binding 0.86 6.18 0.03977
0006826 P: iron ion transport 1.74 0.10 0.03977
0009001 F: serine O-acetyltransferase activity 1.30 0.03 0.04109
0031224 C: intrinsic to membrane 3.08 10.22 0.04240

Bold and italic fonts indicate terms that were over- or under-represented, respectively, in the differentially expressed category, based on false discovery rate (FDR)-corrected Fisher’s exact tests. GO categories: F = function, P = process, C = cellular component.

*Based on number of annotated genes in SD: differentially expressed – 67; non-changing – 6980.

#Based on number of annotated genes in SC: differentially expressed – 234; non-changing – 7289.

Schoville et al.

Schoville et al. BMC Evolutionary Biology 2012 12:170   doi:10.1186/1471-2148-12-170

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