Predicted protein domain organisation derived from cDNA sequences for human and mouse and predicted genes for rat. Pyrin domains are indicated by stippled boxes, and the HIN domain subtypes (A, B or C) are shown. Only a single splice variant is shown for human IFI16 and IFIX, with complete details summarised previously . Mouse p203 also has known splice variants . Regions of sequence similarity among mouse proteins and the relationship between mouse and rat proteins are summarised in Additional Files 1 and 6.
Cridland et al. BMC Evolutionary Biology 2012 12:140 doi:10.1186/1471-2148-12-140