Open Access Highly Accessed Research article

The mammalian PYHIN gene family: Phylogeny, evolution and expression

Jasmyn A Cridland1, Eva Z Curley1, Michelle N Wykes2, Kate Schroder3, Matthew J Sweet3, Tara L Roberts2, Mark A Ragan34, Karin S Kassahn345 and Katryn J Stacey13*

Author Affiliations

1 The University of Queensland, School of Chemistry and Molecular Biosciences, Brisbane, Qld, 4072, Australia

2 Queensland Institute of Medical Research, 300 Herston Road, Brisbane, Qld, 4006, Australia

3 The University of Queensland, Brisbane, Qld, 4072, Australia

4 The University of Queensland, ARC Centre of Excellence in Bioinformatics, Brisbane, Qld, 4072, Australia

5 The University of Queensland, Centre for Medical Genomics, Brisbane, Qld, 4072, Australia

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BMC Evolutionary Biology 2012, 12:140  doi:10.1186/1471-2148-12-140

Published: 7 August 2012

Additional files

Additional file 1:

Figure S1. Diagram of subsequence composition of mouse PYHIN proteins.

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Additional file 2:

Table S1. Sources of sequence data for PYHIN proteins from animals other than mouse, rat and human.

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Additional file 3:

Figure S3. HIN domain alignment.

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Additional file 4:

Figure S4. Pyrin domain alignment.

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Additional file 5:

Figure S5. Evidence for cow, dolphin, llama and sheep AIM2 pseudogenes.

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Additional file 6:

Figure S2. Comparison of mouse and rat PYHIN proteins.

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Additional file 7:

Table S2. Sequences of primers for real time PCR.

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