Table 4

Controlling the effect of gene position.

Gene length

Expression

Recombination


FOPAT

N = 147193 codons

R2 = 0.260***

P(GL)NS,P(Expr)***,

P(dmc1, mre110)***

-0.0480NS

+0.3696***

Co:-0.1064***

nCo:-0.0922***

spo11:-0.0442NS

dmc1:-0.1224***

mre110:-0.0520*

mre116:-0.0922***


FOPGC

N = 180789 codons

R2 = 0.445***

P(GL)NS, P(Expr)***,

P(mre110)*,

P(dmc1)***

-0.1289***

+0.3839***

Co:+3284***

nCo:+0.2472***

spo11:+0.3909***

dmc1:+0.4829***

mre110:+2648***

mre116:+0.2669***


FGCOpt

N = 70401 codons

R2 = 0.174***

P(GL)NS, P(Expr)NS P(dmc1,

mre110)***

-0.0751**

+0.1216***

Co:+0.2735***

nCo:+0.1843***

spo11:+0.3232***

dmc1:+0.3837***

mre110:+0.2104***

mre116:+0.2368***


FGCNon-Opt

N = 126878 codons

R2 = 0.224***

P(GL)NS, P(Expr)***

P(dmc1,

mre110)***

-0.0481NS

+0.0410NS

Co:+0.2990***

nCo:+0.2339***

spo11:+0.3506***

dmc1:+0.4390***

mre110:+0.2311***

mre116:+0.2754***


Spearman Rank Correlations between frequencies of optimal and GC-ending codons with gene length, expression, and various recombination measures after controlling for a potential effect of gene position. The same 1571 genes were used for all measures. Presented are also MR results of variables whose log-transformation did not grossly deviate from a normal distribution. *P < 0.05, **P < 0.01,***P < 0.001

Stoletzki BMC Evolutionary Biology 2011 11:93   doi:10.1186/1471-2148-11-93

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