Gene circuits exploring a genotype network find genotypes with novel alternative phenotypes faster than new genotype networks. The figure shows mean values for 200 independent ensembles of circuits. Ensemble size M = 5 × 103 circuits with N = 16 genes, interaction density c ≈ 0.35, and a fraction d of gene activity differences between s0 and equal to 0.125.
Espinosa-Soto et al. BMC Evolutionary Biology 2011 11:5 doi:10.1186/1471-2148-11-5