Figure 2.

Comparative genomic structure of the D. melanogaster, Ae. aegypti and An. gambiae dsx genes. Comparative genomic structure of the D. melanogaster, Ae. aegypti and An. gambiae dsx genes. Green boxes represent the OD1 and OD2 domain-encoding exons. Black boxes represent exons encoding protein regions conserved in mosquitoes but not in fruit flies. Alternative male-specific and female-specific exons are represented as blue boxes and pink boxes, respectively. Green dots represent canonical acceptor/donor splicing sites. Red dots represent weak acceptor/donor splicing sites. White and green rectangles represent, respectively, TRA/TRA-2 binding sites and Nasonia dsxRE. In Drosophila, the Dmdsx gene is located in a 45-kb region on chromosome 3R and is organized into six exons and five introns, with three common exons followed by a female-specific and two male-specific exons. DmdsxF translation initiates at the AUG within exon 2 and terminates within the female-specific exon 4, while in the case of DmdsxM, translation begins at the same AUG and terminates within the first male-specific exon 5.

Salvemini et al. BMC Evolutionary Biology 2011 11:41   doi:10.1186/1471-2148-11-41
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