Open Access Research article

Genomic organization and splicing evolution of the doublesex gene, a Drosophila regulator of sexual differentiation, in the dengue and yellow fever mosquito Aedes aegypti

Marco Salvemini1, Umberto Mauro12, Fabrizio Lombardo3, Andreina Milano1, Vincenzo Zazzaro1, Bruno Arcà34, Lino C Polito15 and Giuseppe Saccone1*

Author Affiliations

1 Department of Biological Sciences - Section of Genetics and Molecular Biology. University of Naples "Federico II" - Italy

2 CDF - Centro Diagnostico Flegreo, Naples - Italy

3 Department of Public Health - Parasitology Section. University of Rome "La Sapienza" - Italy

4 Department of Structural and Functional Biology. University of Naples "Federico II" - Italy

5 Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" CNR Naples - Italy

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BMC Evolutionary Biology 2011, 11:41  doi:10.1186/1471-2148-11-41

Published: 10 February 2011

Additional files

Additional file 1:

Table S1 Modified Censor output table of repetitive elements identified in Aeadsx intronic regions.

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Additional file 2:

Figure S1 Censor analysis on Aeadsx introns. Censor software graphically maps detected repeats with color-coding of different types of repeats. Legend of Censor output is available at: http://www.girinst.org/censor/help.html#MAP webcite.

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Additional file 3:

Figure S3 Microsynteny analysis. Syntenic dsx-containing regions of Aedes aegypti and Anopheles gambiae are reported. In red the position of putative genes.

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Additional file 4:

Tables S2 Putative cis-acting elements identified in Aeadsx and homologous elements in D. melanogaster, An. gambiae and N. vitripennis. Bold letters indicate identical positions respect to the sequences of Drosophila or Nasonia elements.

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