Table 2

Identification of the domain location of each positively selected site

Number of sites under positive selection identified in each domain of gene


Gene

No. of species

Total no. of sitesa

Domainsb


Signal

LRR-NT

LRR

LRR-CT

Transmembrane

TIR


TLR1

17

2

---

---

2

---

---

---


TLR2

23

6

1

---

3

---

1

1


TLR3

20

9

3

---

3

---

1

2


TLR4

19

22

---

---

19

1

1

1


TLR5

17

7

1

---

3

---

---

3


TLR6

20

3

---

---

---

---

2

1


TLR7

21

7

---

---

7

---

---

---


TLR8

18

26

---

1

25

---

---

---


TLR9

21

4

---

---

4

---

---

---


TLR10

13

7

---

---

5

1

---

1


a total number of sites under selection.

b In comparison with the delimitation of human domains of each TLR gene.

Areal et al. BMC Evolutionary Biology 2011 11:368   doi:10.1186/1471-2148-11-368

Open Data