Additional file 8.

Human GPH-related gene paralogous gene sets and ancestral chordate and vertebrate proto-chromosome relics. Observed boundaries of the paralogous gene sets comprising the GPH subunit-related genes in human compared to segments (S) or conserved vertebrate linkages (CVL) predicted to derive from the two whole genome duplication events of, respectively, ancestral chordate proto-chromosomes (proto-chr.) G and D, according to [45] and of ancestral vertebrate proto-chromosomes 11 and 13/14 according to [44]. [GPH╬▓] tetra-paralogon seems to correspond to the sum of the segments derived from proto-chr. 13 (given in red) and 14.

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Dos Santos et al. BMC Evolutionary Biology 2011 11:332   doi:10.1186/1471-2148-11-332