Table 1

Paralogous pairs with divergent functions

Paralogous pairs

Paralogy definition

DiceM coefficient

Correlation of the expression levels


Enzyme 1

Enzyme 2

Need

Ens

Wap

YBP

KEGG

Pearson coeff.

P value


YBR149W

YHR104W

Y

Y

N

0

N/A

0.68

2.2-16


YDL080C

YDR380W

Y

Y

Y

0.67

0

0.08

0.033


YDL246C

YLR070C

Y

Y

Y

N/A

0

N/A

N/A


YDR147W

YLR133W

Y

Y

N

0

0.5

0.09

0.02


YDR380W

YGR087C

Y

Y

Y

0.54

0

-0.07

0.065


YDR380W

YLR044C

Y

Y

Y

0.54

0

0.08

0.047


YDR380W

YLR134W

Y

Y

Y

0.54

0

0.01

0.76


YDR399W

YJR133W

Y

Y

Y

0

N/A

0.25

7.6-11


YHR123W

YNL130C

Y

Y

Y

0

0

0.50

2.2-16


YJR159W

YLR070C

Y

Y

Y

N/A

0

0.38

2.2-16


Only pairs identified as paralogs by at least by two paralogy definitions (Need: sequence identity above 30%; Ens: derived from the Ensembl database; Wap: listed by Wapinski et al. [13] ) and with a DiceM coefficient equal to 1 in at least one metabolic network are shown. The complete set of data is shown in Additional file 2.

Grassi and Tramontano BMC Evolutionary Biology 2011 11:301   doi:10.1186/1471-2148-11-301

Open Data