Table 4

Divergence times for major split in the Plasmodium timetree with a comprehensive data set including Lemurs and Gorillas

Calibrations: node 73, min 6, max 14.3;

MDT

BEAST


Divergence

Node

Node age (Mya)

95% CrI

Node age (Mya)

95% CrI

cCrIs


Origin of Southern Asia Macaca species

72

8.57

5.75-11.06

5.17

2.63-8.45

2.63-11.06

Split P. cynomologi-P. vivax

68

5.25

3.23-7.44

2.61

0.89-4.64

0.89-7.44

Origin Catarrhini parasite (excluding P. ovale)

74

19.97

13.93-26.49

12.97

7.54-20.73

7.54-26.49

Split Papio/Macaca

73

12.68

9.13-14.25

8.44

6.00-12.83

6.00-14.25

Lorisiforms-Catarrhini parasite

76

24.66

16.95-34.10

17.90

9.91-28.94

9.91-34.10

Radiation Lorisiforms parasite

61

20.91

13.98-29.11

14.87

7.62-24.30

7.62-29.11

Radiation Apes parasite

54

17.36

10.54-26.35

14.13

6.99-23.65

6.99-26.35

Radiation Rodents parasite

57

16.15

9.61-24.29

10.20

4.19-17.65

4.19-24.29

Split P. falciparum-P. reichenowi

46

9.02

4.18-15.86

5.00

2.23-8.55

2.23-15.86

Origin of P. falciparum in humans

40

1.35

0.26-3.63

0.56

0.14-1.10

0.14-3.63

Origin of P. falciparum in humans & bonobos

41

2.94

0.83-6.78

1.21

0.39-2.23

0.39-6.78

Origin of Plasmodium in mammals

78

31.29

21.48-44.16

25.29

13.67-40.79

13.67-44.16

Calibrations: node 73, min 6, max 14.3; node 74, min 23.5

MDT

BEAST


Divergence

Node

Node age (Mya)

95% CrI

Node age (Mya)

95% CrI

cCrIs


Origin of Southern Asia Macaca species

72

8.89

6.51, 11.34

8.61

6.22, 11.13

6.22-11.34

Split P. cynomologi-P. vivax

68

5.42

3.58, 7.56

4.56

2.41, 7.01

2.41-7.56

Origin Catarrhini parasite (excluding P. ovale)

74

25.51

23.56, 30.95

25.85

23.50, 30.25

23.5-30.95

Split Papio/Macaca

73

13.57

11.87, 14.28

12.86

10.59, 14.30

10.59-14.30

Lorisiforms-Catarrhini parasite

76

31.84

26.93, 41.43

33.47

26.66, 41.47

26.66-41.47

Radiation Lorisiforms parasite

61

27.06

21.83, 35.49

27.72

20.11, 35.73

20.11-35.73

Radiation Apes parasite

54

22.90

16.05, 32.70

25.23

15.85, 34.44

15.85-34.44

Radiation Rodents parasite

57

21.37

14.88, 30.11

18.28

10.08, 27.59

10.08-30.11

Split P. falciparum-P. reichenowi

46

12.37

6.48, 20.06

8.97

5.23, 13.33

5.23-20.06

Origin of P. falciparum in humans

40

1.95

0.40, 5.08

0.98

0.32, 1.78

0.32-5.08

Origin of P. falciparum in humans & bonobos

41

4.25

1.34, 9.19

2.15

0.92, 3.54

0.92-9.19

Origin of Plasmodium in mammals

78

39.80

32.22, 52.77

46.09

33.74, 58.74

33.74-58.74


Time estimates and their credibility intervals (CrIs) were estimated with MultiDivTime (MDT) and BEAST using two calibration points (6-14.3 Mya for the pathogens of Papio and Macaca; and a minimum of 23.5 for the divergence of the pathogens of human and macaques). Combined CrIs (cCrIs) are also shown. Node numbers refer to additional file 7.

Pacheco et al. BMC Evolutionary Biology 2011 11:299   doi:10.1186/1471-2148-11-299

Open Data