Nucleotide sequence asymmetry and mRNA abundance for 15 SSD pairs in the S. cerevisiae genome. The sequence asymmetry at the nucleotide level is expressed as the log10(unique sites in the derived paralog/unique sites in the ancestral paralog) and relative RNA abundance is expressed as the log10(RNA count for ancestral paralog/RNA count for derived paralog). There is a significant correlation between divergence between paralogs at the sequence level and divergence in their expression profiles (as represented by mRNA abundance) (Kendall's tau = 0.74; p < 0.0002).
Bu et al. BMC Evolutionary Biology 2011 11:279 doi:10.1186/1471-2148-11-279