Figure 4.

Intron/exon structures of GPRC5 receptor sequences from different species. The exon sizes are drawn to scale. Introns are all shown in the same size. Intron-exon structures for mouse and human are taken from the "Consensus CDS (CCDS)" project, since this database only includes protein coding regions that are consistently annotated and of high quality. "?" in Petromyzon GPRC5 indicates that the 3' sequence is incomplete in the database. Transmembrane domains are indicated in grey, the signal peptides (predicted with SignalP 3.0) are indicated in black.