Additional file 3.

Proteins from Archea genomes containing a RING domain. Putative proteins with a RING domain in eukaryotic, bacterial, and archea genomes were identified using the SUPERFAMILY database. Hundreds of proteins in eukaryotic and bacterial genomes were identified and were not further analyzed. Three positive archea hits were subsequently analyzed using PFAM, InterProScan, and SMART for confirmation. In addition, predicted secondary structure was analyzed using JPRED and PSIPRED. Predicted consensus secondary structure is displayed over the sequences with arrows representing β-sheets and ovals representing α-helices. The conserved cysteine residues are highlighted in red. Protein identification numbers are: Nitrosopumilus maritimus-YP_001581408.1, Methanosarcina acetivorans-NP_617583.1, and Methanosarcina barkeri-YP_306007.1.

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Romá-Mateo et al. BMC Evolutionary Biology 2011 11:225   doi:10.1186/1471-2148-11-225