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Open Access Research article

Evidence for a high mutation rate at rapidly evolving yeast centromeres

Douda Bensasson

Author Affiliations

Faculty of Life Sciences, University of Manchester, Manchester, UK

BMC Evolutionary Biology 2011, 11:211  doi:10.1186/1471-2148-11-211

Published: 18 July 2011

Additional files

Additional file 1:

Figure S1: BensassonSI.pdf contains all the supplementary information for this study; Supplementary Text: Low error rate in Sanger Genome Resequencing Project and this study; Table S1: Primers used to amplify each centromere locus and for DNA sequencing; Table S2: Testing for evidence of recombination using LDhat and four-gamete analysis of centromeres in S. cerevisiae; Table S3: LDhat and four-gamete analysis of centromeres regions, but excluding centromeres themselves; Figure S1: Centromeres and their immediate flanking DNA are too diverged to align S. cerevisiae and S. paradoxus; Figure S2: Centromeres and their immediate flanking DNA are highly diverged between S. cerevisiae and S. mikatae.

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