O. dioica histone gene complement. Histone clusters consist of 2-5 genes dispersed throughout the genome (loci given as roman numerals). Genes belonging to a given cluster were transcriptionally co-regulated and developmental expression profiles of the clusters are indicated with icons (key: H, hatching; ETP, early tadpole; TS, tailshift; D3/4/5, day 3/4/5). Expression of histone genes is mostly driven from short bidirectional promoters, with the exception of several replacement variants (H3.3, H2A.Z, H1.4, H1.3 and CenH3) dispersed as orphan genes. Expression was undetectable for a truncated H3 (H3sh, cluster VIII), likely to be a pseudogene. Light grey arrows indicate non-histone genes.
Moosmann et al. BMC Evolutionary Biology 2011 11:208 doi:10.1186/1471-2148-11-208