Figure 1.

Genes with evidence of recombination are enriched in three COG functional categories. The abscissa represents different COG functional categories. The ordinate represents the proportion of genes in each COG category. Bars in dark gray stand for proportions of genes (n = 365) with evidence for recombination (FDR < 10%). Bars in white stand for proportions of all core genes (n = 1,587) of A. pleuropneumoniae used in this study. Asterisks mark certain COG categories that significantly enriched with recombining genes (P < 0.05, Binomial test). The COG categories are coded as follows: J, translation; K, transcription; L, DNA replication, recombination and repair; D, cell division and chromosome partitioning; V, defense mechanisms; T, signal transduction; M, cell wall/membrane biogenesis; U, intracellular trafficking, secretion and vesicular transport; O, posttranslational modification, protein turnover and chaperones; C, energy production and conversion; G, carbohydrate transport and metabolism; E, amino acid transport and metabolism; F, nucleotide transport and metabolism; H, coenzyme metabolism; I, lipid metabolism; P, inorganic ion transport and metabolism; Q, secondary metabolites biosynthesis, transport and catabolism; R, general functional prediction only; S, function-unassigned conserved proteins; -, unknown proteins not in the COG collection.