Average Hamming distance at the error catastrophe when robustness distribution changes. The quality factor of each sequence depends on the Hamming distance with the master sequence k, according to qk = q if k ≤ kc and qk = 1 - Kq(1 - q) if k > kc . In this case kc = 10. Thus, Kq is a parameter that modifies the quality factor and the robustness of the Hamming classes. (see text for details). The amplification and degradation factors of the master, and mutant sequences as well as the sequence length are the same as in figure 2.
Tejero et al. BMC Evolutionary Biology 2011 11:2 doi:10.1186/1471-2148-11-2