Hamming class fraction vs the selection coefficient (s). The amplification factors of the master sequence, i.e. the zero Hamming class, is Am = 10, and that of every other Hamming class Hi is Ai = 2. The degradation factor is the same for all the Hamming classes and is D = 1. The sequence length is ν = 20. The selection coefficient is evaluated following equation 6, that is to say considering the mutant phenotype as a whole, not taking into account that it is composed by Hamming classes.
Tejero et al. BMC Evolutionary Biology 2011 11:2 doi:10.1186/1471-2148-11-2