Open Access Research article

Natural selection among Eurasians at genomic regions associated with HIV-1 control

Yann C Klimentidis1*, Brahim Aissani2, Mark D Shriver3, David B Allison1 and Sadeep Shrestha2

Author Affiliations

1 Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA

2 Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA

3 Department of Anthropology, Pennsylvania State University, University Park, PA 16802, USA

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BMC Evolutionary Biology 2011, 11:173  doi:10.1186/1471-2148-11-173

Published: 20 June 2011

Additional files

Additional file 1:

GSFST percentile for top ten non-HLA 'hits' among African Americans. Window size (Kb) is on the x-axis while GSFST percentile in on the y-axis, for windows centered on the top ten non-HLA 'hits' in the African-American GWAS.

Format: DOCX Size: 32KB Download file

Open Data

Additional file 2:

GSFST percentile for top ten non-HLA 'hits' among European Americans. Window size (Kb) is on the x-axis while GSFST percentile in on the y-axis, for windows centered on the top ten non-HLA 'hits' in the European-American GWAS.

Format: DOCX Size: 32KB Download file

Open Data

Additional file 3:

Q-Q plots of REHH p-values by group. Observed vs. expected -log10 p-values for REHH in seven groups, considered in the 31.1. to 37.3 Mb region of chromosome 6. P-values are empirical, based on the distribution of all REHH p-values for all of chromosome 6.

Format: DOCX Size: 86KB Download file

Open Data

Additional File 4:

Details of HGDP sample. A listing of the 53 populations in the HGDP sample and how they were grouped.

Format: DOCX Size: 11KB Download file

Open Data