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Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving

Rachele Cagliani, Stefania Riva, Uberto Pozzoli, Matteo Fumagalli, Giacomo P Comi, Nereo Bresolin, Mario Clerici and Manuela Sironi*

BMC Evolutionary Biology 2011, 11:171  doi:10.1186/1471-2148-11-171

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