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Open Access Research article

Evolution of the mammalian lysozyme gene family

David M Irwin12*, Jason M Biegel3 and Caro-Beth Stewart3

Author Affiliations

1 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

2 Banting and Best Diabetes Centre, University of Toronto, Toronto, Canada

3 Department of Biological Sciences, University at Albany, State University of New York, Albany, New York 12222, USA

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BMC Evolutionary Biology 2011, 11:166  doi:10.1186/1471-2148-11-166

Published: 15 June 2011

Additional files

Additional file 1:

Supplementary Table 1. This file is in PDF format. Location of lysozyme genes in vertebrate genomes.

Format: PDF Size: 264KB Download file

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Additional file 2:

Supplementary Figure 1. This file is in PDF format. Phylogeny of vertebrate lysozyme-like sequences generated by PhyloBayes.

Format: PDF Size: 271KB Download file

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Additional file 3:

Supplementary Figure 2. This file is in PDF format. Phylogeny of vertebrate lysozyme-like sequences generated by PhyML.

Format: PDF Size: 306KB Download file

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Additional file 4:

Supplementary Figure 3. This file is in PDF format. Phylogeny of only mammalian lysozyme-like sequences generated by MrBayes with support for the orthologous genes by different phylogenetic methods.

Format: PDF Size: 224KB Download file

This file can be viewed with: Adobe Acrobat Reader

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Additional file 5:

Supplementary Figure 4. This file is in PDF format. Conservation of genomic organization near Lyzl1/2 genes.

Format: PDF Size: 327KB Download file

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Additional file 6:

Supplementary Figure 5. This file is in PDF format. Conservation of genomic organization near Lyzl4 genes.

Format: PDF Size: 313KB Download file

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Additional file 7:

Supplementary Figure 6. This file is in PDF format. Phylogeny of Lyzl4 genes.

Format: PDF Size: 142KB Download file

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Additional file 8:

Supplementary Figure 7. This file is in PDF format. Conservation of genomic organization near Lyzl6 genes.

Format: PDF Size: 328KB Download file

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Additional file 9:

Supplementary Figure 8. This file is in PDF format. Phylogeny of Lyzl6 genes.

Format: PDF Size: 151KB Download file

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Additional file 10:

Supplementary Figure 9. This file is in PDF format. Conservation of genomic organization near Spaca3 genes.

Format: PDF Size: 304KB Download file

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Additional file 11:

Supplementary Figure 10. This file is in PDF format. Phylogeny of Spaca3 genes.

Format: PDF Size: 151KB Download file

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Additional file 12:

Supplementary Figure 11. This file is in PDF format. Conservation of genomic organization near Spaca5 genes.

Format: PDF Size: 308KB Download file

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Additional file 13:

Supplementary Figure 12. This file is in PDF format. Phylogeny of Spaca5 genes.

Format: PDF Size: 151KB Download file

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Additional file 14:

Supplementary Figure 13. This file is in PDF format. Phylogeny of Lalba genes.

Format: PDF Size: 157KB Download file

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Additional file 15:

Supplementary Figure 14. This file is in PDF format. Conservation of genomic sequences between Lalba and c12orf41 genes.

Format: PDF Size: 264KB Download file

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Additional file 16:

Supplementary Figure 15. This file is in PDF format. DNA sequences of Lysc1 genes.

Format: PDF Size: 120KB Download file

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Additional file 17:

Supplementary Figure 16. This file is in PDF format. Phylogeny of Lysc1 genes.

Format: PDF Size: 121KB Download file

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Additional file 18:

Supplementary Table 2. This file is in PDF format. Outgroup lysozyme sequences used for phylogenetic analysis.

Format: PDF Size: 99KB Download file

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Additional file 19:

Supplementary Figure 17. This file is in Word format. FASTA formatted MAFFT alignment of lysozyme DNA sequences

Format: DOC Size: 220KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data