Schematic representation of the splicing mechanisms generating IgD and their relationship with the genomic sequence. Examples of the four RNA splicing found in EST database are indicated. All ESTs are membrane antibodies. Only OLGI31I09 presents all exons to code for a chimeric transmembrane IgD with a Cμ1 domain. Furthermore, mRNA without variable region (OLSP26E01, OLKI34N15 and OLSP22P22) were found, all of them have stop codons in all reading frames.
Magadán-Mompó et al. BMC Evolutionary Biology 2011 11:165 doi:10.1186/1471-2148-11-165