Additional file 1.
Overview of the GSIS network. Reactions are represented as arrows (which may be uni- or bidirectional) and labelled in green v1 to v53 according to  which also provides a key to abbreviations. Metabolites are labelled in black. Enzymes catalysing reactions are labelled in brown.
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Ainali et al. BMC Evolutionary Biology 2011 11:142 doi:10.1186/1471-2148-11-142