Table 4

Selection tests over all sites, antigen binding sites (ABS) and non-antigen binding sites (non-ABS)

Sites


Locus

All

ABS

Non-ABS


N

81

20

61

dN/dS

0.302

n/a*

0.202

DRA

Z; dN dS

0.143

0.121

0.096

Z; dN >dS

1

0.058

1

Z; dN <dS

0.074

1

0.049


N

67

18

49

dN/dS

0.990

1.013

0.915

DQA

Z; dN dS

0.975

0.978

0.715

Z; dN >dS

1

0.489

1

Z; dN <dS

0.488

1

0.359


N = number of codons; dN/dS = synonymous to non-synonymous rate ratio; Z test p-values for rejecting the null hypothesis of neutrality (dN = dS) for the alternative hypotheses of non-neutrality (dN dS), positive selection (dN >dS), and purifying selection (dN <dS).* There were no synonymous mutations, therefore dN/dS is undefined.

Kamath and Getz BMC Evolutionary Biology 2011 11:128   doi:10.1186/1471-2148-11-128

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