Table 3

Amino acid physicochemical properties under positive destabilizing selection in fru C3 exon.

Physicochemical property

Goodness-of-fit

(neutral expectation)

radical change category

(6, 7 e 8)

z-score


Alpha-helical tendencies (Pα)

36.498***

8

1.975*

Average number of surrounding residues (Ns)

76.820***

-

-

Beta-structure tendencies (Pβ)

67.631***

-

-

Bulkiness (Bl)

40.169***

-

-

Buriedness (Br)

47.688***

-

-

Chromatographic index (Rf)

65.981***

-

-

Coil tendencies (Pc)

82.908***

-

-

Composition (C)

52.020***

-

-

Compressibility (K0)

36.874***

-

-

Equilibrium constant (ionization of COOH) (pK')

33.814***

-

-

Helical contact area (Ca)

41.651***

-

-

Hydropathy (H)

92.128***

6

4.972***

Isoelectric point (pHi)

56.298***

-

-

Long-range non-bonded energy (El)

38.021***

-

-

Mean r.m.s. fluctuation displacement (F)

57.826***

-

-

Molecular volume (Mv)

48.275***

-

-

Molecular weight (Mw)

53.230***

6

3.928***

Normalized consensus hydrophobicity (Hnc)

29.042***

-

-

Partial specific volume (V0)

22.173**

-

-

Polar requirement (Pr)

77.854***

-

-

Polarity (P)

117.046***

-

-

Power to be at the C-terminal of alpha-helix (αc)

57.177***

-

-

Power to be at the middle of alpha-helix (αm)

40.309***

-

-

Power to be at the N-terminal of alpha-helix (αn)

35.782***

-

-

Refractive index (μ)

17.263*

-

-

Short and medium range non-bonded energy (Esm)

73.460***

-

-

Solvent accessible reduction ratio (Ra)

16.175*

-

-

Surrounding hydrophobicity (Hp)

90.284***

-

-

Thermodynamic transfer hydrophobicity (Ht)

90.401***

-

-

Total non-bonded energy (Et)

32.042***

-

-

Turn tendencies (Pt)

45.706***

-

-


* p < 0.05; ** p < 0.01; *** p < 0.001

Sobrinho and de Brito BMC Evolutionary Biology 2010 10:293   doi:10.1186/1471-2148-10-293

Open Data