Table 4

Core haplotypes with significant REHH values in Africans involving FOXI1

H^a

REHH

Frequency

Distance (bp)^b

Distance (cM)^c

Core haplotype

Genes in core regionⁱ

P value

q value^j

0.02

19.58

0.528

80443

0.056

ACCC^d

DOCK2, FOXI1

0.8 × 10^-5

0.0038

0.04

16.93

0.528

61086

0.026

ACCC^d

DOCK2, FOXI1

0.3 × 10^-5

0.0016

0.04

12.08

0.590

-64129

-0.058

AGC^e

FOXI1

0.6 × 10^-4

0.0213

0.04

8.32

0.675

-41241

-0.051

AG^f

DOCK2, FOXI1

0.8 × 10^-4

0.0247

0.04

10.42

0.528

55531

0.028

A^g

DOCK2, FOXI1

0.8 × 10^-4

0.0191

0.04

10.65

0.561

-54967

-0.053

CTG^h

DOCK2, FOXI1

1.2 × 10^-4

0.0215

^aDegree to which each added marker at a further distance causes the extended haplotypes to decay for all core haplotypes

^bPhysical distance (bp) from the core at which the signal has been captured. (-) indicates downstream direction. Otherwise upstream

^cGenetic distance (cM) from the core at which the signal has been captured. (-) indicates downstream direction. Otherwise upstream

^drs7736379, rs6872596, rs4449553, rs17562083

^ers7729440, rs2879278, rs11134616

^frs4867919, rs11134612

^grs1501644

^hrs7709558, rs12515896, rs6861611

ⁱGenes within ±100 kb around the core are considered

^jExpected proportion of false positives among all significant p values

Moreno-Estrada et al. BMC Evolutionary Biology 2010 10:267   doi:10.1186/1471-2148-10-267