Phylogenetic analysis of mole β-like globin genes. Maximum likelihood phylograms depicting relationships among mammalian β-like globin genes based on (A) 477 bp of coding sequence, and (B) 938 bp of intron 2. With the exception of the sequences from eastern mole (Scalopus aquaticus) and coast mole (Scapanus orarius), all β-like globin sequences were retrieved from full genome assemblies (see text for details). Both trees demonstrate that the β-like globin genes of Scalopus and Scapanus are orthologous to the HBD genes of other mammals. Because mammals typically possess multiple tandemly duplicated copies of adult beta-like globin genes, we index each paralog with the symbol -T followed by a number that corresponds to the 5' to '3' linkage order. Pseudogene sequences are indicated by the suffix 'ps'.
Campbell et al. BMC Evolutionary Biology 2010 10:214 doi:10.1186/1471-2148-10-214