Research article
Redundancy of myostatin and growth/differentiation factor 11 function
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* Corresponding authors: Alexandra C McPherron mcpherrona@niddk.nih.gov - Se-Jin Lee sjlee@jhmi.edu
1 Genetics of Development and Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
2 Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
BMC Developmental Biology 2009, 9:24 doi:10.1186/1471-213X-9-24
Published: 19 March 2009Additional files
Additional file 1:
Cranial and forelimb digit skeletal defects in Mstn-/- Gdf11-/- newborn mice. (A and B) Skull phenotype of Gdf11-/- (A) and Mstn-/- Gdf11-/- (B) pups. Double mutants have a rounded frontal bone (arrow). Forelimb digit phenotype of Gdf11-/- (C) and Mstn-/- Gdf11-/- (D) pups. Digit identity is labeled with roman numerals. Note the fusion of digits III and IV and the supernumerary digit V (V*) in the double mutant.
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