Increased thermotolerance from BD is independent of age and maintained upon return to a control diet. (A) BD increases survival at 38°C, relative to control fed (CF) animals at 7, 18, or 22 days of age. Error bars are standard error of the mean. (B) Thermotolerance (survival at 38°C) is significantly increased at the 12th day of adulthood relative to CF animals, regardless of whether BD is initiated at the 4th (BD4–12) or 8th (BD8–12) day of adulthood. Transient BD from the 4th to the 8th day of adulthood (BD4–8) also results in enhanced thermotolerance relative to CF animals.
Smith et al. BMC Developmental Biology 2008 8:49 doi:10.1186/1471-213X-8-49