Figure 1.

The effects of dietary restriction on C. elegans life history traits. (A) Kaplan-Maier survival curves showing the longevity of C. elegans under excess (closed circles), high (open circles) and low food (closed squares) environments (see Material and Methods). Significance is shown for excess, high, and low food, from Log Rank tests n/censored individuals 175/22, 204/110 and 238/189 respectively. (B) Daily fecundity of C. elegans under excess (closed circles), high (open circles) and low food (closed squares) environments. (C) Total fecundity of C. elegans under excess, high and low food environments; n = 36, 44 and 35 respectively. (D) Growth curves of C. elegans under excess (closed circles), high (open circles) and low food (squares) environments, n = 49, 38, and 21 respectively. Images show representative adults from high food (upper panel) and low food (lower panel) treatments. Scale bar indicates 100 μm. (E) Hypodermal (hyp7) cell number of young adult C. elegans under high and low food environments; n = 10 and 9 respectively. (F) Hypodermal (hyp7) ploidy of C. elegans (120 h) under excess, high and low food environments; n = 19, 254, and 189 respectively. All error bars show 95% confidence intervals, and asterisk show level of significance, *** shows P < 0.0001, by ANOVA.

Tain et al. BMC Developmental Biology 2008 8:28   doi:10.1186/1471-213X-8-28
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