mfr mutations affect Gurken localization during oogenesis. These confocal images compare a stage 10 egg chamber produced by a bw;st female (top panels) to one produced by a mfrZ4070/mfrZ1386 female (bottom panels). Gurken (green) was detected by immunolocalization in dorsal-anterior corner of the wild-type oocyte (A) and in a more restricted region in the oocyte produced by mfr females (C). Nuclei were visualized by DAPI staining (blue) (B and D). Arrows indicate oocyte nucleus. Scale bars are approximately 50 microns.
Smith and Wakimoto BMC Developmental Biology 2007 7:21 doi:10.1186/1471-213X-7-21