Table 2

Genes showing 2-fold or greater changes in mineralized zone

Gene Name

Gene Description

Fold Change (CNP/Control)


Ptgs2

prostaglandin-endoperoxide synthase 2

2.87

Bcan

brevican

2.75

Gabrb3

gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3

2.46

Robo4

roundabout homolog 4 (Drosophila)

2.31

Cd38

CD38 antigen

2.23

Lepr

leptin receptor

2.22

Cd24a

CD24a antigen

2.15

Tgfbi

transforming growth factor, beta induced

2.14

Tmem56

transmembrane protein 56

2.12

Gsg2

germ cell-specific gene 2

2.11

Dspg3

dermatan sulphate proteoglycan 3

2.11

Siat4c

sialyltransferase 4C (beta-galactoside alpha-2,3-sialytransferase)

2.04

Hbb-y

hemoglobin Y, beta-like embryonic chain

0.21

Zbtb8

zinc finger and BTB domain containing 8

0.24

Chic1

cysteine-rich hydrophobic domain 1

0.27

Mia

EGL nine homolog 2 (C. elegans)

0.28

Nox4

NADPH oxidase 4

0.29

Fgd6

FYVE, RhoGEF and PH domain containing 6

0.32

Ddc

dopa decarboxylase

0.34

Crxos1

Crx opposite strand transcript 1

0.37

Hapln1

cartilage link protein 1

0.37

Col27a1

procollagen, type XXVII, alpha 1

0.38

Fgd5

FYVE, RhoGEF and PH domain containing 5

0.38

Msi2h

Musashi homolog 2 (Drosophila)

0.39

Rgs11

regulator of G-protein signaling 11

0.42

Mrpl35

mitochondrial ribosomal protein L35

0.43

Wwp2

WW domain containing E3 ubiquitin protein ligase 2

0.44

Glt25d2

glycosyltransferase 25 domain containing 2

0.44

Zcchc5

zinc finger, CCHC domain containing 5

0.45

Stno

strawberry notch homolog (Drosophila)

0.46

Ppp1r3c

protein phosphatase 1, regulatory (inhibitor) subunit 3C

0.46

Col9a3

procollagen, type IX, alpha 3

0.47

Igf2

insulin-like growth factor 2

0.47

Edil3

EGF-like repeats and discordin I-like domains 3

0.48

Ttll3

tubulin tyrosine ligase-like family, member 3

0.48

A2m

alpha-2-macroglobulin

0.49

Ctf1

cardiotrophin 1

0.49

Xist

inactive X specific transcripts

0.49

Zfp458

zinc finger protein 458

0.50


Agoston et al. BMC Developmental Biology 2007 7:18   doi:10.1186/1471-213X-7-18

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