Figure 5.

Effects of pimozide on the Ca²⁺ influx stimulated by hZP. Spermatozoa were capacitated in the presence or absence of 10 μM pimozide. They were then loaded with Fura-2 in BWW medium and hZP (2/μl) was added (n = 3 experiments). The results are expressed as the mean ± SEM of Ca²⁺ influx induced by hZP, for the peak and the sustained phase; *p < 0.001, Mann and Whitney test.