Table 1

Leading Edge polarisation deficits in the heart region of the dorsal vessel

Genotype

yw

mys1

scb2

mys RNAi

scb RNAi

n (per genotype)


Embryos with CB displacement

4

16

12

10

12

20 embryos

Apical/Non-Apical Slit

8.6 ± 1.2

2.6 ± 0.3

1.8 ± 0.1

2.2 ± 0.2

2.1 ± 0.1

9 embryos

Leading Edge Activity, %

41 ± 3

12 ± 2

16 ± 3

42 ± 2

36 ± 3

12 LEs


Slit apicalisation is expressed as a ratio of the average immunofluorescence intensity in the apical region, divided by the intensity of non- apical heart fluorescence. Means shown ± standard error. Data sets significantly different from yw or yw, UAS-moe-mCherry/+, tup-GFP, dMEF-GAL4/+ controls are in bold italic if p < .001 and in bold if p < .05 by Mann-Whitney U test

Vanderploeg et al. BMC Developmental Biology 2012 12:8   doi:10.1186/1471-213X-12-8

Open Data